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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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Angiotensin I-13C6,15N (human, mouse, rat) TFA is a 13C and 15N labeled compound. It is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE). This product is for research use only.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
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Capric acid (DA Decanoic acid Decylic acid) a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil contributes to seizure control through direct AMPA receptor inhibition Capric acid is also a modulating ligand for PPARs Due to its specific melting range the product may be solid liquid a solidified melt or a supercooled melt
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